PCOS and Depression: Understanding the Link and Treatment Options

Individuals with PCOS are at a higher risk for living with depression. However, there are treatment options available to help manage symptoms.

📷 Image by Marina Vitale

Are you tired of feeling like you’re on an emotional roller coaster? Dealing with the symptoms of Polycystic Ovary Syndrome (PCOS) can be challenging enough, but when you add depression into the mix, it can feel like an uphill battle. Don’t worry, though! There is hope, and treatment options are available to help you maintain your overall well-being. Let’s dive into the connection between PCOS and depression, explore treatment options, and provide valuable insights to help you navigate this journey.

💔 Can PCOS cause depression?

The answer is, unfortunately, yes. Researchers have found that individuals with PCOS are more prone to depression due to the unpleasant symptoms associated with the condition. In fact, studies have shown that up to 26% of PCOS patients also experience depression [^1]. 🤯

Some potential factors contributing to depression in individuals with PCOS include:

Hormonal changes

PCOS disrupts the delicate hormonal balance in the body, leading to an increase in androgens, a group of sex hormones. This hormonal imbalance can result in hair loss, acne, weight gain, and excessive hair growth [^1]. These physical changes can negatively affect self-esteem and body image, potentially contributing to depression.

Irregular menstrual cycle

Many individuals with PCOS experience irregular or absent menstrual periods. The hormonal imbalance and lack of predictability can be frustrating and impact mental well-being. If you’re experiencing menstrual cycles longer than 35-40 days or skipping periods altogether, it’s essential to seek evaluation from a healthcare professional [^1].


The same hormonal imbalance that causes PCOS can also lead to infertility. PCOS is one of the most common causes of infertility, and the inability to conceive can lead to feelings of sadness and depression [^1].

Weight gain

PCOS can affect metabolism, increasing the risk of insulin resistance, diabetes, and weight gain. The fluctuation in weight, combined with other physical symptoms, can take a toll on mental health [^1]. It’s a vicious cycle!

🚀 Treatment options to consider

Treating PCOS is a complex process as the condition affects each individual differently. It’s crucial to work with a healthcare professional to determine the best course of action for your unique situation. While there is no definitive cure for PCOS, various options can help alleviate symptoms and improve your overall well-being. Let’s explore some treatment options:

Lifestyle changes

Eating a healthy diet, engaging in regular exercise, getting enough sleep, and managing weight are crucial steps in managing PCOS symptoms [^1]. It might seem overwhelming, but incorporating small changes into your routine can make a big difference. Don’t hesitate to seek guidance from a mental health professional to help with lifestyle changes and to manage your mental health while making these adjustments.


Several medications can help with PCOS management. Metformin, commonly prescribed for type 2 diabetes, can also improve insulin resistance in individuals with PCOS. Inositol, a dietary supplement, is also being studied for its potential benefits in regulating insulin [^1]. Speak with your medical provider to determine which medication is the right fit for you based on your medical history and desired fertility outcomes.

Fertility treatments

If you’re trying to conceive, fertility treatments can be an option. Clomiphene citrate, letrozole, gonadotropins, intrauterine insemination (IUI), and in vitro fertilization (IVF) are some of the choices available [^1]. It’s essential to weigh the risks and benefits of these treatments with your doctor before proceeding.


Sometimes, antidepressants may be prescribed to help alleviate the mental health symptoms of PCOS. However, it’s essential to consider the potential side effects, such as weight gain, which can worsen PCOS symptoms [^1]. Consult with a mental health specialist to discuss the options and potential risks before starting any antidepressant medication.


Psychotherapy can be an effective tool in addressing and managing depression in individuals with PCOS. Therapies like acceptance and commitment therapy (ACT) and cognitive-behavioral therapy (CBT) have shown promising results [^1]. Tools like the FindCare resource can help you find a therapist who can provide the support you need.

Seeking support

Remember, you’re not alone in this journey! If you’re experiencing depression alongside your PCOS symptoms, consider reaching out to a mental health professional. Signs that you may need help include disrupted sleeping or eating patterns, relationship troubles, feelings of worthlessness or hopelessness, and thoughts of self-harm or suicide [^1]. Don’t hesitate to seek help and support when needed.

🤝 Your mental health matters

PCOS and depression are serious matters that require attention and care. It’s essential to prioritize your mental health alongside managing the physical symptoms of PCOS. Your journey might have ups and downs, but with the right support and treatment, you can navigate through it. If you’re looking for a support network, consider visiting The National Polycystic Ovary Syndrome Association for valuable resources and connections [^1].

Remember, you’re strong, and you have what it takes to tackle PCOS and depression. Share this article with someone who needs to hear this message! 💪

📚 Reference List

  1. National Institutes of Health: PCOS and Depression