Combining Erectile Dysfunction and Chest Pain Drugs: A Risky Mix for Your Heart
A recent study suggests that the simultaneous use of erectile dysfunction drugs, such as Viagra, Levitra, Cialis, and certain chest pain medications, could potentially raise the risk of cardiovascular death.
A combo of meds for chest pain and erectile dysfunction may increase the chance of heart failure.

Taking erectile dysfunction drugs in combination with some medications for chest pain may increase cardiovascular risk, research suggests. Alexey Kuzma/Stocksy
Introduction: A Heartbreaking Combination
Did you know that combining medications for erectile dysfunction (ED) and angina (chest pain) could put your heart health at risk? A recent study from Sweden reveals that taking both types of drugs simultaneously can double the blood vessel dilating effects, leading to a dangerous drop in blood pressure. This combination significantly increases the chances of cardiac events and even death. So, let’s dive deeper into this topic to understand the potential dangers and precautions associated with these medications.
The Study: Double Trouble
The study analyzed data from 61,487 men and found that those who were taking both ED medications and nitrates for angina were far more likely to experience adverse cardiovascular events. Compared to men receiving nitrates only, their risk of mortality increased by 39%, cardiovascular mortality by 34%, and non-cardiovascular mortality by 40%. Additionally, they were 72% more likely to have a heart attack, 67% more likely to experience heart failure, 95% more likely to require cardiac revascularization, and 70% more likely to experience major cardiac events. This research is published in the Journal of the American College of Cardiology.
The Link between Erectile Dysfunction and Heart Health
While many men perceive ED drugs only as enhancers of sexual function, these medications actually serve as indicators of potential heart health issues, according to Dr. Ylva Trolle Lagerros of the Karolinska Institute, the study’s first author. ED can be a clinical marker for future heart problems, often considered a “harbinger for cardiovascular events.” The underlying cause behind both conditions is vascular disease, involving a combination of atherosclerosis and endothelial dysfunction. Atherosclerosis refers to the buildup of cholesterol plaque on artery walls, narrowing them and affecting blood flow. Endothelial dysfunction, on the other hand, describes the hardening of the endothelial cells lining blood vessel walls, negatively impacting their flexibility and capacity to accommodate blood flow.
The Danger of Chest Pain: Angina and Its Relation to the Heart
Chest pain, or angina, is a common symptom of heart-related issues. Dr. Yu-Ming Ni, a board-certified general cardiologist, explains that cholesterol plaque build-up in the arteries of the heart can lead to inadequate blood flow during times of stress or increased oxygen demand, such as during exercise or sexual activity. In these scenarios, blocked arteries hinder blood flow, resulting in pain and discomfort. It’s crucial to address both ED and angina promptly, as they can be intertwined manifestations of the same basic process: vascular disease.
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The Conflict between ED and Chest Pain Medications
ED drugs, known as phosphodiesterase type 5 inhibitors (PDE5i), improve blood flow by temporarily dilating blood vessels. Nitrates, on the other hand, also dilate blood vessels. While each medication individually lowers blood pressure, their combined effect can be dangerously amplified. To ensure patient safety, doctors recommend discontinuing either the nitrate or the ED medication if they are taken together. It’s essential to consult with a healthcare professional to determine the best course of action.
Safer Alternatives: Exploring Options for Angina
Although PDE5i drugs are the recommended treatment for ED, alternatives to nitrates for angina are available. Dr. Glenn N. Levine suggests three basic types of antianginal therapy as potential alternatives. Additionally, adopting healthier lifestyle habits, such as quitting smoking, regular physical activity, and a balanced diet rich in fruits, vegetables, and fish, may improve both ED and angina symptoms. Addressing obesity, which may contribute to ED and various cardiovascular precursors, could also positively impact erectile function.
Monitoring Medications: A Tricky Task
Monitoring the safety of drug interactions can be challenging for doctors due to the sporadic nature of ED medication usage. Patients often fail to include these medications on their lists, leading to potential risks. The involvement of pharmacists in reviewing medication lists and discussing additional medications with patients can enhance patient safety.
Q&A Section: Readers’ Concerns Addressed
Q: Are there any other medications besides nitrates that can be used to treat angina?
A: Yes, in addition to nitrates, there are alternative options available for treating angina. Consult your healthcare provider to explore which alternative therapy best suits your individual needs.
Q: Can obesity contribute to both ED and heart problems?
A: Yes, obesity is associated with a variety of cardiovascular risk factors, including erectile dysfunction. By addressing obesity and adopting a healthier lifestyle, you can positively impact both conditions.
Q: Are there any lifestyle changes that can help alleviate angina symptoms?
A: Absolutely! Quitting smoking, engaging in regular physical activity, and following a healthy diet can significantly improve angina symptoms. Incorporating more fruits, vegetables, and fish into your meals is particularly beneficial.
Conclusion: Protecting Your Heart
Educating ourselves about potential risks and taking necessary precautions is crucial in safeguarding our heart health. Combining medications for erectile dysfunction and chest pain can have serious consequences, including an increased likelihood of cardiac events and mortality. Remember, early detection and timely intervention can make all the difference. If you have any concerns or questions, always reach out to your healthcare provider. Stay informed, stay healthy, and let’s keep our hearts thriving!
Reference Links: – Combining Erectile Dysfunction and Angina Drugs May Increase Cardiovascular Risk (Medical News Today) – Heart Failure: Erectile Dysfunction Plus Chest Pain Drugs May Up Risk (Pinterest) – Stem Cell Therapy Boosts Quality of Life for People with Advanced Heart Failure (3Health) – Essential Traits to Keep College Kids Happy (3Health) – 15 Natural Ways to Lower Your Blood Pressure (3Health) – Protect Your Erection: 11 Tips to Help Prevent Erectile Dysfunction (3Health) – Unapproved Fat-Dissolving Injections Leaving Patients Maimed, FDA Warns (3Health) – Americans Will Pay $35 Per Month for Insulin by 2024 (3Health)
Remember to consult your healthcare provider for personalized medical advice.
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