Skip the Zaps: New Research Suggests Some Women Can Sidestep Radiation for Breast Cancer Treatment

Study Shows Select Older Women with Early-Stage Breast Cancer Can Forego Radiotherapy Safely

Older women with early-stage breast cancer may not need radiotherapy, according to a new study.

By Ernie Mundell, HealthDay Reporter

Women in their 50s and 60s who have experienced the joys and quirks of menopause may have reason to celebrate. A recent study reveals that for those diagnosed with early stage HR+ breast cancers (the most common type), skipping radiation therapy might be a safe and viable option.

But let’s back up a bit. HR+ breast cancer refers to tumors that contain hormone receptors for estrogen or progesterone. So, for postmenopausal women with this type of tumor, the usual treatment consists of a lumpectomy (surgical removal of the tumor) followed by a combination of radiation therapy and hormonal treatments.

However, recent studies have sparked interest in exploring whether radiation therapy can be omitted for certain patients. Previous research focused on older adults aged 65 and above, suggesting that they can skip radiation without compromising outcomes. Now, the latest study from Emory University in Atlanta suggests that this might hold true for younger postmenopausal women as well.

Presenting their findings at the prestigious San Antonio Breast Cancer Symposium (SABCS), Dr. Reshma Jagsi and her team at Emory University found that younger postmenopausal patients aged 50 to 69 with stage 1 breast cancer who choose to skip radiation therapy after lumpectomy have an extremely low risk of disease recurrence within five years.

To arrive at this conclusion, the researchers conducted genetic tests to assess the likelihood of tumor recurrence in each patient. Women determined to have a low risk of recurrence were given the option to skip radiation therapy while continuing five years of hormonal treatments. The results were impressive: out of the 186 patients evaluated, 100% were still alive after five years, with 99% remaining cancer-free.

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However, let’s not jump to conclusions just yet. While the short-term outlook is promising, Jagsi cautions that it’s essential to gather more long-term data to determine the safety and feasibility of omitting radiation therapy in this age group.

Nevertheless, Jagsi believes that these findings provide valuable insights and decision-making tools for women diagnosed with breast cancer. Patients can regain some sense of control and empowerment in choosing their treatment options when armed with knowledge and multiple choices.

So, what can we take away from this study? For women in their 50s and 60s facing early stage HR+ breast cancer, skipping radiation therapy might be a safe bet. However, it’s crucial to consult with your medical team and consider the individual characteristics of your tumor before making any decisions.

Remember, ladies, knowledge is power, and humor can be healing. Stay informed, stay positive, and stay in control.

More information

For more information on breast cancer, its various types, and treatment options, visit the U.S. National Cancer Institute.

SOURCES: San Antonio Breast Cancer Symposium, news release, Dec. 7, 2023